Ontology highlight
ABSTRACT:
SUBMITTER: Nishiguchi A
PROVIDER: S-EPMC7434010 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Biomacromolecules 20200413 6
Targeted delivery of antigens to immune cells using micro/nanocarriers may serve as a therapeutic application for vaccination. However, synthetic carriers have potential drawbacks including cytotoxicity, low encapsulation efficiency of antigen, and lack of a morphological design, which limit the translation of the delivery system to clinical use. Here, we report a carrier-free and three-dimensional (3D)-shape-designed antigen nanoparticle by multiphoton lithography-based 3D-printing. This simple ...[more]