Ontology highlight
ABSTRACT:
SUBMITTER: Girgis CM
PROVIDER: S-EPMC4083371 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Girgis Christian M CM Mokbel Nancy N Digirolamo Douglas J DJ
Current osteoporosis reports 20140601 2
Musculoskeletal diseases are highly prevalent with staggering annual health care costs across the globe. The combined wasting of muscle (sarcopenia) and bone (osteoporosis)-both in normal aging and pathologic states-can lead to vastly compounded risk for fracture in patients. Until now, our therapeutic approach to the prevention of such fractures has focused solely on bone, but our increasing understanding of the interconnected biology of muscle and bone has begun to shift our treatment paradigm ...[more]