Ontology highlight
ABSTRACT:
SUBMITTER: Cao J
PROVIDER: S-EPMC4085799 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Cao Jian J Liu Xiangtao X Han Shizhong S Zhang Clarence K CK Liu Zongzhi Z Li Dawei D
Human genetics 20131101 3
Positive genetic associations of rs6313 (102T/C at exon 1) and rs6311 (-1438A/G) on the 5-hydroxytryptamine (serotonin) 2A receptor gene (HTR2A or 5-HT2A) were reported for alcohol and drug abuse; however, other association studies failed to produce consistent results supporting the susceptibility of the two single nucleotide polymorphisms (SNPs). To clarify the associations of the HTR2A gene with substance use disorders, we performed a meta-analysis based on the genotypes from the available can ...[more]