Ontology highlight
ABSTRACT:
SUBMITTER: Montagna C
PROVIDER: S-EPMC4086474 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Montagna Costanza C Di Giacomo Giuseppina G Rizza Salvatore S Cardaci Simone S Ferraro Elisabetta E Grumati Paolo P De Zio Daniela D Maiani Emiliano E Muscoli Carolina C Lauro Filomena F Ilari Sara S Bernardini Sergio S Cannata Stefano S Gargioli Cesare C Ciriolo Maria R MR Cecconi Francesco F Bonaldo Paolo P Filomeni Giuseppe G
Antioxidants & redox signaling 20140513 4
<h4>Aims</h4>Nitric oxide (NO) production is implicated in muscle contraction, growth and atrophy, and in the onset of neuropathy. However, many aspects of the mechanism of action of NO are not yet clarified, mainly regarding its role in muscle wasting. Notably, whether NO production-associated neuromuscular atrophy depends on tyrosine nitration or S-nitrosothiols (SNOs) formation is still a matter of debate. Here, we aim at assessing this issue by characterizing the neuromuscular phenotype of S ...[more]