Ontology highlight
ABSTRACT:
SUBMITTER: Molino NM
PROVIDER: S-EPMC4087095 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Molino Nicholas M NM Wang Szu-Wen SW
Current opinion in biotechnology 20140108
Caged protein nanoparticles possess many desirable features for drug delivery, such as ideal sizes for endocytosis, non-toxic biodegradability, and the ability to functionalize at three distinct interfaces (external, internal, and inter-subunit) using the tools of protein engineering. Researchers have harnessed these attributes by covalently and non-covalently loading therapeutic molecules through mechanisms that facilitate release within specific microenvironments. Effective delivery depends on ...[more]