Ontology highlight
ABSTRACT:
SUBMITTER: Mitchell MJ
PROVIDER: S-EPMC7717100 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Mitchell Michael J MJ Billingsley Margaret M MM Haley Rebecca M RM Wechsler Marissa E ME Peppas Nicholas A NA Langer Robert R
Nature reviews. Drug discovery 20201204 2
In recent years, the development of nanoparticles has expanded into a broad range of clinical applications. Nanoparticles have been developed to overcome the limitations of free therapeutics and navigate biological barriers - systemic, microenvironmental and cellular - that are heterogeneous across patient populations and diseases. Overcoming this patient heterogeneity has also been accomplished through precision therapeutics, in which personalized interventions have enhanced therapeutic efficac ...[more]