Ontology highlight
ABSTRACT:
SUBMITTER: Vollrath F
PROVIDER: S-EPMC4088128 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Vollrath Fritz F Hawkins Nick N Porter David D Holland Chris C Boulet-Audet Maxime M
Scientific reports 20140709
Here we present a set of measurements using Differential Scanning Fluorimetry (DSF) as an inexpensive, high throughput screening method to investigate the folding of silk protein molecules as they abandon their first native melt conformation, dehydrate and denature into their final solid filament conformation. Our first data and analyses comparing silks from spiders, mulberry and wild silkworms as well as reconstituted 'silk' fibroin show that DSF can provide valuable insights into details of si ...[more]