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Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities.

ABSTRACT:

Background

Little is known about the epidemiology of basal cell carcinoma (BCC).

Methods

Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case-control analysis, we examined lifestyle factors and comorbidities.

Results

Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight.

Conclusions

Basal cell carcinoma places a growing public health burden. Lifestyle factors do not play a major role in pathogenesis, but immunosuppression is important.

SUBMITTER: Reinau D

PROVIDER: S-EPMC4090732 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Publications

Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities.

Reinau D D Surber C C Jick S S SS Meier C R CR

British journal of cancer 20140529 1

<h4>Background</h4>Little is known about the epidemiology of basal cell carcinoma (BCC).<h4>Methods</h4>Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case-control analysis, we examined lifestyle factors and comorbidities.<h4>Results</h4>Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight.<h4> ...[more]

PMID: 24874476

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