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A polymer-based ratiometric intracellular glucose sensor.


ABSTRACT: The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated.

SUBMITTER: Zhang L 

PROVIDER: S-EPMC4093769 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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A polymer-based ratiometric intracellular glucose sensor.

Zhang Liqiang L   Su Fengyu F   Buizer Sean S   Kong Xiangxing X   Lee Fred F   Day Kevin K   Tian Yanqing Y   Meldrum Deirdre R DR  

Chemical communications (Cambridge, England) 20140701 52


The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated. ...[more]

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