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A polymer-based ratiometric intracellular glucose sensor.

ABSTRACT: The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated.

SUBMITTER: Zhang L

PROVIDER: S-EPMC4093769 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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A polymer-based ratiometric intracellular glucose sensor.

Zhang Liqiang L Su Fengyu F Buizer Sean S Kong Xiangxing X Lee Fred F Day Kevin K Tian Yanqing Y Meldrum Deirdre R DR

Chemical communications (Cambridge, England) 20140701 52

The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated. ...[more]

PMID: 24840577

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