Ontology highlight
ABSTRACT:
SUBMITTER: Wood CR
PROVIDER: S-EPMC4096978 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Wood Christopher R CR Rosenbaum Joel L JL
Current biology : CB 20140508 10
The cilium is a specialized extension of the cell in which many specific proteins are admitted and retained, while many others are excluded or expelled. In order to maintain the organelle, the cell must possess mechanisms for the selective gating of protein entry, as well as for the targeted transport of proteins to the cilium from their sites of synthesis within the cell [1-4]. We hypothesized that the cell employs cytoplasmic vesicles as vehicles not only for the transport of proteins destined ...[more]