Ontology highlight
ABSTRACT:
SUBMITTER: Humphreys DP
PROVIDER: S-EPMC4097441 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Clinical and vaccine immunology : CVI 20140430 7
Antibodies for the treatment of Clostridium difficile infection (CDI) have been demonstrated to be effective in the research and clinical environments. Early uncertainties about molecular and treatment modalities now appear to have converged upon the systemic dosing of mixtures of human IgG1. Although multiple examples of high-potency monoclonal antibodies (MAbs) exist, significant difficulties were initially encountered in their discovery. This minireview describes historical and contemporary M ...[more]