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Predicted configurations of oligosaccharide extensions in the lipooligosaccharide of nontypeable Haemophilus influenzae isolates.


ABSTRACT: Lipooligosaccharide configurations were predicted in nontypeable Haemophilus influenzae isolates based on the presence of seven oligosaccharide extension-initiating genes (or alleles). Predicted configurations with 2 to 3 oligosaccharide extensions were more prevalent among middle ear than throat strains. In addition, strains with these configurations averaged higher levels of serum resistance than strains with other configurations.

SUBMITTER: McCrea KW 

PROVIDER: S-EPMC4097733 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Predicted configurations of oligosaccharide extensions in the lipooligosaccharide of nontypeable Haemophilus influenzae isolates.

McCrea Kirk W KW   Xie Jingping J   Daniel Deborah D   Ulrich-Lewis Justin Theophilus JT   Zhang Lixin L  

Journal of clinical microbiology 20140430 7


Lipooligosaccharide configurations were predicted in nontypeable Haemophilus influenzae isolates based on the presence of seven oligosaccharide extension-initiating genes (or alleles). Predicted configurations with 2 to 3 oligosaccharide extensions were more prevalent among middle ear than throat strains. In addition, strains with these configurations averaged higher levels of serum resistance than strains with other configurations. ...[more]

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