Spatiotemporal specificity in cholinergic control of neocortical function.
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ABSTRACT:
SUBMITTER: Munoz W
PROVIDER: S-EPMC4100208 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Spatiotemporal specificity in cholinergic control of neocortical function.
Muñoz William W Rudy Bernardo B
Current opinion in neurobiology 20140315
Cholinergic actions are critical for normal cortical cognitive functions. The release of acetylcholine (ACh) in neocortex and the impact of this neuromodulator on cortical computations exhibit remarkable spatiotemporal precision, as required for the regulation of behavioral processes underlying attention and learning. We discuss how the organization of the cholinergic projections to the cortex and their release properties might contribute to this specificity. We also review recent studies sugges ...[more]
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