Ontology highlight
ABSTRACT:
SUBMITTER: Sara T
PROVIDER: S-EPMC4101727 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Sára Tomáš T Schwarz Thomas C TC Kurzbach Dennis D Wunderlich Christoph H CH Kreutz Christoph C Konrat Robert R
ChemistryOpen 20140618 3
Protein-protein interactions are of utmost importance to an understanding of biological phenomena since non-covalent and therefore reversible couplings between basic proteins leads to the formation of complex regulatory and adaptive molecular systems. Such systems are capable of maintaining their integrity and respond to external stimuli, processes intimately related to living organisms. These interactions, however, span a wide range of dissociation constants, from sub-nanomolar affinities in ti ...[more]