Ontology highlight
ABSTRACT:
SUBMITTER: Jiang DK
PROVIDER: S-EPMC4105840 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Nature genetics 20121216 1
To identify genetic susceptibility loci for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) in the Chinese population, we carried out a genome-wide association study (GWAS) in 2,514 chronic HBV carriers (1,161 HCC cases and 1,353 controls) followed by a 2-stage validation among 6 independent populations of chronic HBV carriers (4,319 cases and 4,966 controls). The joint analyses showed that HCC risk was significantly associated with two independent loci: rs7574865 at STAT4, P(meta ...[more]