Ontology highlight
ABSTRACT:
SUBMITTER: Towheed A
PROVIDER: S-EPMC4106415 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Towheed Atif A Markantone Desiree M DM Crain Aaron T AT Celotto Alicia M AM Palladino Michael J MJ
Neurobiology of disease 20140505
Endogenous mitochondrial genes encode critical oxidative phosphorylation components and their mutation results in a set of disorders known collectively as mitochondrial encephalomyopathies. There is intensive interest in modulating mitochondrial function as organelle dysfunction has been associated with numerous disease states. Proteins encoded by the mitochondrial genome cannot be genetically manipulated by current techniques. Here we report the development of a mitochondrial-targeted RNA expre ...[more]