Ontology highlight
ABSTRACT:
SUBMITTER: Peng SC
PROVIDER: S-EPMC4106832 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Peng Shih-Chi SC Liao Chun-Ta CT Peng Chien-Hua CH Cheng Ann-Joy AJ Chen Shu-Jen SJ Huang Chung-Guei CG Hsieh Wen-Ping WP Yen Tzu-Chen TC
PloS one 20140722 7
MicroRNAs (miRNAs) have a major impact on regulatory networks in human carcinogenesis. In this study, we sought to investigate the prognostic significance of miRNAs in patients with oral cavity squamous cell carcinoma (OSCC). In a discovery phase, RNA was extracted from 58 OSCC tumor samples and paired normal tissues. MiRNAs expression was evaluated with TaqMan Array Card and TaqMan MicroRNA assays. The prognostic significance of the miRNA signature identified in the discovery phase was validate ...[more]