Ontology highlight
ABSTRACT:
SUBMITTER: Jiang L
PROVIDER: S-EPMC4203242 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Jiang Lin L Wang Chaofu C Sun Canlin C Xu Yumin Y Ding Zhongqi Z Zhang Xueling X Huang Junxing J Yu Hong H
International journal of clinical and experimental pathology 20140815 9
MicroRNA-218 (miR-218) acts as a tumor suppressor in numerous types of cancer by regulation of the expression of target genes. The aim of this study was to investigate whether polymorphisms in miR-218 LAMB3 pathway were associated with the risk and prognosis of esophageal squamous cell carcinoma (ESCC). Pri-mir-218 rs11134527 and LAMB3 rs2566 were genotyped in ESCC patients and 745 controls to assess their associations with cancer risk and overall survival. Pri-mir-218 rs11134527 was significant ...[more]