Ontology highlight
ABSTRACT:
SUBMITTER: Johannesson B
PROVIDER: S-EPMC4107326 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Johannesson Bjarki B Sattler Susanne S Semenova Ekaterina E Pastore Saveria S Kennedy-Lydon Teresa M TM Sampson Robert D RD Schneider Michael D MD Rosenthal Nadia N Bilbao Daniel D
Disease models & mechanisms 20140801 8
Allergic contact dermatitis (ACD) is triggered by an aberrant hyperinflammatory immune response to innocuous chemical compounds and ranks as the world's most prevalent occupational skin condition. Although a variety of immune effector cells are activated during ACD, regulatory T (Treg) cells are crucial in controlling the resulting inflammation. Insulin-like growth factor-1 (IGF-1) regulates cell proliferation and differentiation and accelerates wound healing and regeneration in several organs i ...[more]