Dataset Information

Pooled analysis of non-union, re-operation, infection, and approach related complications after anterior odontoid screw fixation.

ABSTRACT:

Background

Anterior odontoid screw fixation (AOSF) has been one of the most popular treatments for odontoid fractures. However, the true efficacy of AOSF remains unclear. In this study, we aimed to provide the pooled rates of non-union, reoperation, infection, and approach related complications after AOSF for odontoid fractures.

Methods

We searched studies that discussed complications after AOSF for type II or type III odontoid fractures. A proportion meta-analysis was done and potential sources of heterogeneity were explored by meta-regression analysis.

Results

Of 972 references initially identified, 63 were eligible for inclusion. 54 studies provided data regarding non-union. The pooled non-union rate was 10% (95% CI: 7%-3%). 48 citations provided re-operation information with a pooled proportion of 5% (95% CI: 3%-7%). Infection was described in 20 studies with an overall rate of 0.2% (95% CI: 0%-1.2%). The main approach related complication is postoperative dysphagia with a pooled rate of 10% (95% CI: 4%-17%). Proportions for the other approach related complications such as postoperative hoarseness (1.2%, 95% CI: 0%-3.7%), esophageal/retropharyngeal injury (0%, 95% CI: 0%-1.1%), wound hematomas (0.2%, 95% CI: 0%-1.8%), and spinal cord injury (0%, 95% CI: 0%-0.2%) were very low. Significant heterogeneities were detected when we combined the rates of non-union, re-operation, and dysphagia. Multivariate meta-regression analysis showed that old age was significantly predictive of non-union. Subgroup comparisons showed significant higher non-union rates in age ≥ 70 than that in age ≤ 40 and in age 40 to <50. Meta-regression analysis did not reveal any examined variables influencing the re-operation rate. Meta-regression analysis showed age had a significant effect on the dysphagia rate.

Conclusions/significances

This study summarized the rates of non-union, reoperation, infection, and approach related complications after AOSF for odontoid fractures. Elderly patients were more likely to experience non-union and dysphagia.

SUBMITTER: Tian NF

PROVIDER: S-EPMC4109995 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Pooled analysis of non-union, re-operation, infection, and approach related complications after anterior odontoid screw fixation.

Tian Nai-Feng NF Hu Xu-Qi XQ Wu Li-Jun LJ Wu Xin-Lei XL Wu Yao-Sen YS Zhang Xiao-Lei XL Wang Xiang-Yang XY Chi Yong-Long YL Mao Fang-Min FM

PloS one 20140724 7

<h4>Background</h4>Anterior odontoid screw fixation (AOSF) has been one of the most popular treatments for odontoid fractures. However, the true efficacy of AOSF remains unclear. In this study, we aimed to provide the pooled rates of non-union, reoperation, infection, and approach related complications after AOSF for odontoid fractures.<h4>Methods</h4>We searched studies that discussed complications after AOSF for type II or type III odontoid fractures. A proportion meta-analysis was done and po ...[more]

PMID: 25058011

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Dataset Information

Pooled analysis of non-union, re-operation, infection, and approach related complications after anterior odontoid screw fixation.

Background

Methods

Results

Conclusions/significances

Publications

Pooled analysis of non-union, re-operation, infection, and approach related complications after anterior odontoid screw fixation.

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