Ontology highlight
ABSTRACT:
SUBMITTER: Morris DS
PROVIDER: S-EPMC4113789 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Morris David S DS Prevelige Peter E PE
Viruses 20140714 7
Bacteriophage P22 has long been considered a hallmark model for virus assembly and maturation. Repurposing of P22 and other similar virus structures for nanotechnology and nanomedicine has reinvigorated the need to further understand the protein-protein interactions that allow for the assembly, as well as the conformational shifts required for maturation. In this work, gp5, the major coat structural protein of P22, has been manipulated in order to examine the mutational effects on procapsid stab ...[more]