Ontology highlight
ABSTRACT:
SUBMITTER: Parent KN
PROVIDER: S-EPMC2951021 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20100301 3
Viral capsid assembly and stability in tailed, dsDNA phage and Herpesviridae are achieved by various means including chemical crosslinks (unique to HK97), or auxiliary proteins (lambda, T4, phi29, and herpesviruses). All these viruses have coat proteins (CP) with a conserved, HK97-like core structure. We used a combination of trypsin digestion, gold labeling, cryo-electron microscopy, 3D image reconstruction, and comparative modeling to derive two independent, pseudoatomic models of bacteriophag ...[more]