Ontology highlight
ABSTRACT:
SUBMITTER: Butler LM
PROVIDER: S-EPMC4116070 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Butler Lynn M LM Dzabic Mensur M Bakker Frank F Davoudi Belghis B Jeffery Hannah H Religa Piotr P Bojakowski Krzysztof K Yaiw Koon-Chu KC Rahbar Afsar A Söderberg-Naucler Cecilia C
Journal of the American Society of Nephrology : JASN 20140410 8
Anemia is a feature of CKD and a complication of renal transplantation, often caused by impaired production of erythropoietin. The kidney is a target organ for human cytomegalovirus (hCMV) in such patients, but it is not known whether hCMV effects erythropoietin production. We found that kidneys from patients with CKD were positive for hCMV protein and that blood levels of hCMV IgG inversely correlated with red blood cell count. In mice, systemic murine cytomegalovirus infection decreased serum ...[more]