Ontology highlight
ABSTRACT:
SUBMITTER: Prilutsky D
PROVIDER: S-EPMC4117413 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Trends in molecular medicine 20131224 2
The elucidation of disease etiologies and establishment of robust, scalable, high-throughput screening assays for autism spectrum disorders (ASDs) have been impeded by both inaccessibility of disease-relevant neuronal tissue and the genetic heterogeneity of the disorder. Neuronal cells derived from induced pluripotent stem cells (iPSCs) from autism patients may circumvent these obstacles and serve as relevant cell models. To date, derived cells are characterized and screened by assessing their n ...[more]