Ontology highlight
ABSTRACT:
SUBMITTER: Balch CM
PROVIDER: S-EPMC4121330 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Balch Charles M CM Soong Seng-jaw SJ Gershenwald Jeffrey E JE Thompson John F JF Coit Daniel G DG Atkins Michael B MB Ding Shouluan S Cochran Alistair J AJ Eggermont Alexander M M AM Flaherty Keith T KT Gimotty Phyllis A PA Johnson Timothy M TM Kirkwood John M JM Leong Stanley P SP McMasters Kelly M KM Mihm Martin C MC Morton Donald L DL Ross Merrick I MI Sondak Vernon K VK
Annals of surgical oncology 20130710 12
<h4>Background</h4>We postulated that the worse prognosis of melanoma with advancing age reflected more aggressive tumor biology and that in younger patients the prognosis would be more favorable.<h4>Materials and methods</h4>The expanded AJCC melanoma staging database contained 11,088 patients with complete data for analysis, including mitotic rate.<h4>Results</h4>With increasing age by decade, primary melanomas were thicker, exhibited higher mitotic rates, and were more likely to be ulcerated. ...[more]