Ontology highlight
ABSTRACT:
SUBMITTER: Takeuchi K
PROVIDER: S-EPMC4125369 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Takeuchi Kenichiro K Ohishi Maki M Endo Keiko K Suzumura Kenichi K Naraoka Hitoshi H Ohata Takeji T Seki Jiro J Miyamae Yoichi Y Honma Masashi M Soga Tomoyoshi T
Biomarker insights 20140727
Gastrointestinal symptoms are a common manifestation of adverse drug effects. Non-steroid anti-inflammatory drugs (NSAIDs) are widely prescribed drugs that induce the serious side effect of gastric mucosal ulceration. Biomarkers for these side effects have not been identified and ulcers are now only detectable by endoscopy. We previously identified five metabolites as biomarker candidates for NSAID-induced gastric ulcer using capillary electrophoresis-mass spectrometry (CE-MS)-based metabolomic ...[more]