Ontology highlight
ABSTRACT:
SUBMITTER: Cai Q
PROVIDER: S-EPMC4127632 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Nature genetics 20140720 8
In a three-stage genome-wide association study among East Asian women including 22,780 cases and 24,181 controls, we identified 3 genetic loci newly associated with breast cancer risk, including rs4951011 at 1q32.1 (in intron 2 of the ZC3H11A gene; P=8.82×10(-9)), rs10474352 at 5q14.3 (near the ARRDC3 gene; P=1.67×10(-9)) and rs2290203 at 15q26.1 (in intron 14 of the PRC1 gene; P=4.25×10(-8)). We replicated these associations in 16,003 cases and 41,335 controls of European ancestry (P=0.030, 0.0 ...[more]