Ontology highlight
ABSTRACT:
SUBMITTER: Petersen GM
PROVIDER: S-EPMC2853179 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Nature genetics 20100124 3
We conducted a genome-wide association study of pancreatic cancer in 3,851 affected individuals (cases) and 3,934 unaffected controls drawn from 12 prospective cohort studies and 8 case-control studies. Based on a logistic regression model for genotype trend effect that was adjusted for study, age, sex, self-described ancestry and five principal components, we identified eight SNPs that map to three loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Two correlated SNPs, rs9543325 (P = 3.27 x 10(-1 ...[more]