Ontology highlight
ABSTRACT:
SUBMITTER: Hitti J
PROVIDER: S-EPMC4128483 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Hitti Jane J Lapidus Jodi A JA Lu Xinfang X Reddy Ashok P AP Jacob Thomas T Dasari Surendra S Eschenbach David A DA Gravett Michael G MG Nagalla Srinivasa R SR
American journal of obstetrics and gynecology 20100515 1
<h4>Objective</h4>We analyzed the vaginal fluid proteome to identify biomarkers of intraamniotic infection among women in preterm labor.<h4>Study design</h4>Proteome analysis was performed on vaginal fluid specimens from women with preterm labor, using multidimensional liquid chromatography, tandem mass spectrometry, and label-free quantification. Enzyme immunoassays were used to quantify candidate proteins. Classification accuracy for intraamniotic infection (positive amniotic fluid bacterial c ...[more]