Ontology highlight
ABSTRACT:
SUBMITTER: Huang YH
PROVIDER: S-EPMC4129139 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
BioMed research international 20140721
Replication restart primosome is a complex dynamic system that is essential for bacterial survival. This system uses various proteins to reinitiate chromosomal DNA replication to maintain genetic integrity after DNA damage. The replication restart primosome in Escherichia coli is composed of PriA helicase, PriB, PriC, DnaT, DnaC, DnaB helicase, and DnaG primase. The assembly of the protein complexes within the forked DNA responsible for reloading the replicative DnaB helicase anywhere on the chr ...[more]