The role of surface functionality in nanoparticle exocytosis.
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ABSTRACT:
SUBMITTER: Kim CS
PROVIDER: S-EPMC4134693 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Publications
The role of surface functionality in nanoparticle exocytosis.
Kim Chang Soo CS Le Ngoc D B NDB Xing Yuqing Y Yan Bo B Tonga Gulen Yesilbag GY Kim Chaekyu C Vachet Richard W RW Rotello Vincent M VM
Advanced healthcare materials 20140324 8
Getting out is just as important for nano-therapeutics as getting in. Exocytosis rates determine residency time in the cell, an important determinant for therapeutic efficacy and also for eventual clearance from the cell. In this study, it is shown that exocytosis efficiency is determined by surface functionality, providing a strategy for optimizing nanocarriers. ...[more]
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