Ontology highlight
ABSTRACT:
SUBMITTER: Dube DK
PROVIDER: S-EPMC4135462 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Dube Dipak K DK Wang Jushuo J Pellenz Christopher C Fan Yingli Y Dube Syamalima S Han Mingda M Linask Kersti K Sanger Jean M JM Sanger Joseph W JW
Anatomical record (Hoboken, N.J. : 2007) 20140901 9
Several missense mutations in the Z-band protein, myotilin, have been implicated in human muscle diseases such as myofibrillar myopathy, spheroid body myopathy, and distal myopathy. Recently, we have reported the cloning of chicken myotilin cDNA. In this study, we have investigated the expression of myotilin in cross-striated muscles from developing chicken by qRT-PCR and in situ hybridizations. In situ hybridization of embryonic stages shows myotilin gene expression in heart, somites, neural ti ...[more]