Unknown

Dataset Information

0

Expression Pattern of Axin2 During Chicken Development.


ABSTRACT: Canonical Wnt-signalling is well understood and has been extensively described in many developmental processes. The regulation of this signalling pathway is of outstanding relevance for proper development of the vertebrate and invertebrate embryo. Axin2 provides a negative-feedback-loop in the canonical Wnt-pathway, being a target gene and a negative regulator. Here we provide a detailed analysis of the expression pattern in the development of the chicken embryo. By performing in-situ hybridization on chicken embryos from stage HH 04+ to HH 32 we detected a temporally and spatially restricted dynamic expression of Axin2. In particular, data about the expression of Axin2 mRNA in early embryogenesis, somites, neural tube, limbs, kidney and eyes was obtained.

SUBMITTER: Eckei G 

PROVIDER: S-EPMC5040342 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

altmetric image

Publications

Expression Pattern of Axin2 During Chicken Development.

Eckei Gesa G   Böing Marion M   Brand-Saberi Beate B   Morosan-Puopolo Gabriela G  

PloS one 20160928 9


Canonical Wnt-signalling is well understood and has been extensively described in many developmental processes. The regulation of this signalling pathway is of outstanding relevance for proper development of the vertebrate and invertebrate embryo. Axin2 provides a negative-feedback-loop in the canonical Wnt-pathway, being a target gene and a negative regulator. Here we provide a detailed analysis of the expression pattern in the development of the chicken embryo. By performing in-situ hybridizat  ...[more]

Similar Datasets

| S-EPMC4135462 | biostudies-literature
| S-EPMC3093991 | biostudies-literature
| S-EPMC5054732 | biostudies-literature
| S-EPMC4015062 | biostudies-literature
| S-EPMC6234749 | biostudies-literature
| S-EPMC10527692 | biostudies-literature
| S-EPMC2566905 | biostudies-literature
| S-EPMC3272118 | biostudies-literature
| S-EPMC1633734 | biostudies-literature
| S-EPMC6293534 | biostudies-literature