Ontology highlight
ABSTRACT:
SUBMITTER: Eckei G
PROVIDER: S-EPMC5040342 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Eckei Gesa G Böing Marion M Brand-Saberi Beate B Morosan-Puopolo Gabriela G
PloS one 20160928 9
Canonical Wnt-signalling is well understood and has been extensively described in many developmental processes. The regulation of this signalling pathway is of outstanding relevance for proper development of the vertebrate and invertebrate embryo. Axin2 provides a negative-feedback-loop in the canonical Wnt-pathway, being a target gene and a negative regulator. Here we provide a detailed analysis of the expression pattern in the development of the chicken embryo. By performing in-situ hybridizat ...[more]