In vitro antifungal susceptibility profile and correlation of mycelial and yeast forms of molecularly characterized Histoplasma capsulatum strains from India.
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ABSTRACT:
SUBMITTER: Kathuria S
PROVIDER: S-EPMC4135809 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
In vitro antifungal susceptibility profile and correlation of mycelial and yeast forms of molecularly characterized Histoplasma capsulatum strains from India.
Kathuria Shallu S Singh Pradeep K PK Meis Jacques F JF Chowdhary Anuradha A
Antimicrobial agents and chemotherapy 20140630 9
The antifungal susceptibility profiles of the mycelial and yeast forms of 23 Histoplasma capsulatum strains from pulmonary and disseminated histoplasmosis patients in India are reported here. The MIC data of this dimorphic fungus had good agreement between both forms for azoles, amphotericin B, and caspofungin. Therefore, the use of mycelial inocula for H. capsulatum antifungal susceptibility testing is suggested, which is less time-consuming vis-à-vis the yeast form, which requires 6 to 8 weeks ...[more]
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