Ontology highlight
ABSTRACT:
SUBMITTER: Tagg KA
PROVIDER: S-EPMC4135994 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20140602 8
Sequencing of pJIE512b, a 92.3-kb IncI1 sequence type 2 (ST2) plasmid carrying bla(CMY-2), revealed a bla(CMY-2) context that appeared to have been mobilized from an IncA/C plasmid by the insertion sequence IS1294. A comparison with published plasmids suggests that bla(CMY-2) has been mobilized from IncA/C to IncI1 plasmids more than once by IS1294-like elements. Alignment of pJIE512b with the only other available IncI1 ST2 plasmid revealed differences across the backbones, indicating variabilit ...[more]