Unknown

Dataset Information

0

Optimize the Separation of Fluorinated Amphiles Using High-Performance Liquid Chromatography.


ABSTRACT: Using the set of fluorinated amphiles that contain the same fluorocarbon moiety but differ in their fluorine content percentage F% (25-45%), the optimal condition for a F%-based separation of these analytes using reverse-phase chromatography was explored. It is found that optimal separation can be achieved by pairing a regular reverse-phase column (such as C8) with a fluorinated eluent (such as trifluoroethanol). Separation is further improved at higher chromatographic temperature with baseline separation achieved at 45°C. This result indicates that the separation of fluorocarbon-tagged molecules can be based on the fluorine content percentage rather than the number of fluorine atoms.

SUBMITTER: Xia G 

PROVIDER: S-EPMC4136531 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Optimize the Separation of Fluorinated Amphiles Using High-Performance Liquid Chromatography.

Xia Guiquan G   Li Yuqi Y   Li Yu Y   Li Xuefei X   Zhang Hua H   Yu Yihua Bruce YB   Jiang Zhong-Xing ZX  

Journal of fluorine chemistry 20140901


Using the set of fluorinated amphiles that contain the same fluorocarbon moiety but differ in their fluorine content percentage F% (25-45%), the optimal condition for a F%-based separation of these analytes using reverse-phase chromatography was explored. It is found that optimal separation can be achieved by pairing a regular reverse-phase column (such as C8) with a fluorinated eluent (such as trifluoroethanol). Separation is further improved at higher chromatographic temperature with baseline  ...[more]

Similar Datasets

| S-EPMC2848510 | biostudies-literature
| S-EPMC1154376 | biostudies-other
| S-EPMC7238425 | biostudies-literature
| S-EPMC2780435 | biostudies-literature
| S-EPMC1148027 | biostudies-other
| S-EPMC9075151 | biostudies-literature
| S-EPMC6323246 | biostudies-literature
| S-EPMC1147900 | biostudies-other
| S-EPMC1154125 | biostudies-other
| S-EPMC5547239 | biostudies-other