Transcriptome instability as a molecular pan-cancer characteristic of carcinomas.
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ABSTRACT:
SUBMITTER: Sveen A
PROVIDER: S-EPMC4137096 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Transcriptome instability as a molecular pan-cancer characteristic of carcinomas.
Sveen Anita A Johannessen Bjarne B Teixeira Manuel R MR Lothe Ragnhild A RA Skotheim Rolf I RI
BMC genomics 20140810
<h4>Background</h4>We have previously proposed transcriptome instability as a genome-wide, pre-mRNA splicing-related characteristic of colorectal cancer. Here, we explore the hypothesis of transcriptome instability being a general characteristic of cancer.<h4>Results</h4>Exon-level microarray expression data from ten cancer datasets were analyzed, including breast cancer, cervical cancer, colorectal cancer, gastric cancer, lung cancer, neuroblastoma, and prostate cancer (555 samples), as well as ...[more]
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2020-02-05 | GSE143152 | GEO