Ontology highlight
ABSTRACT:
SUBMITTER: van 't Erve TJ
PROVIDER: S-EPMC4138246 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
van 't Erve Thomas J TJ Wagner Brett A BA Martin Sean M SM Knudson C Michael CM Blendowski Robyn R Keaton Mignon M Holt Tracy T Hess John R JR Buettner Garry R GR Ryckman Kelli K KK Darbro Benjamin W BW Murray Jeffrey C JC Raife Thomas J TJ
Transfusion 20140306 8
<h4>Background</h4>The degeneration of red blood cells (RBCs) during storage is a major issue in transfusion medicine. Family studies in the 1960s established the heritability of the RBC storage lesion based on poststorage adenosine triphosphate (ATP) concentrations. However, this critical discovery has not been further explored. In a classic twin study we confirmed the heritability of poststorage ATP concentrations and established the heritability of many other RBC metabolites.<h4>Study design ...[more]