Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen TL
PROVIDER: S-EPMC4138752 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Nguyen Thi-Lien TL Kwon Seung-Hwan SH Hong Sa-Ik SI Ma Shi-Xun SX Jung Yang-Hee YH Hwang Ji-Young JY Kim Hyoung-Chun HC Lee Seok-Yong SY Jang Choon-Gon CG
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20140415 10
Transient receptor potential vanilloid type 1 (TRPV1), a nonselective cation channel, is a well-known pain-related receptor. TRPV1 involvement in morphine-induced antinociception, tolerance, and withdrawal symptoms has been previously reported. Emerging evidence indicates that TRPV1 may be related to both the cellular and behavioral effects of addictive drugs. In the present study, we investigated the role of TRPV1 in morphine reward using the conditioned place preference (CPP) paradigm in mice. ...[more]