Ontology highlight
ABSTRACT:
SUBMITTER: Liang J
PROVIDER: S-EPMC4139778 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Liang Jianfeng J Tong Pan P Zhao Wanni W Li Yaqiao Y Zhang Li L Xia Ying Y Yu Yanbing Y
International journal of molecular sciences 20140625 7
Neuroblastoma is the most common and deadly solid tumor in children, and there is currently no effective treatment available for neuroblastoma patients. The repressor element-1 silencing transcription (REST) factor has been found to play important roles in the regulation of neural differentiation and tumorigenesis. Recently, a REST signature consisting of downstream targets of REST has been reported to have clinical relevance in both breast cancer and glioblastoma. However it remains unclear how ...[more]