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ABSTRACT: Objective
To assess the relative impact of an intensive lifestyle intervention (ILI) on use and costs of health care within the Look AHEAD trial.Research design and methods
A total of 5,121 overweight or obese adults with type 2 diabetes were randomly assigned to an ILI that promoted weight loss or to a comparison condition of diabetes support and education (DSE). Use and costs of health-care services were recorded across an average of 10 years.Results
ILI led to reductions in annual hospitalizations (11%, P = 0.004), hospital days (15%, P = 0.01), and number of medications (6%, P < 0.001), resulting in cost savings for hospitalization (10%, P = 0.04) and medication (7%, P < 0.001). ILI produced a mean relative per-person 10-year cost savings of $5,280 (95% CI 3,385-7,175); however, these were not evident among individuals with a history of cardiovascular disease.Conclusions
Compared with DSE over 10 years, ILI participants had fewer hospitalizations, fewer medications, and lower health-care costs.
SUBMITTER: Espeland MA
PROVIDER: S-EPMC4140155 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Espeland Mark A MA Glick Henry A HA Bertoni Alain A Brancati Frederick L FL Bray George A GA Clark Jeanne M JM Curtis Jeffrey M JM Egan Caitlin C Evans Mary M Foreyt John P JP Ghazarian Siran S Gregg Edward W EW Hazuda Helen P HP Hill James O JO Hire Don D Horton Edward S ES Hubbard Van S VS Jakicic John M JM Jeffery Robert W RW Johnson Karen C KC Kahn Steven E SE Killean Tina T Kitabchi Abbas E AE Knowler William C WC Kriska Andrea A Lewis Cora E CE Miller Marsha M Montez Maria G MG Murillo Anne A Nathan David M DM Nyenwe Ebenezer E Patricio Jennifer J Peters Anne L AL Pi-Sunyer Xavier X Pownall Henry H Redmon J Bruce JB Rushing Julia J Ryan Donna H DH Safford Monika M Tsai Adam G AG Wadden Thomas A TA Wing Rena R RR Yanovski Susan Z SZ Zhang Ping P
Diabetes care 20140901 9
<h4>Objective</h4>To assess the relative impact of an intensive lifestyle intervention (ILI) on use and costs of health care within the Look AHEAD trial.<h4>Research design and methods</h4>A total of 5,121 overweight or obese adults with type 2 diabetes were randomly assigned to an ILI that promoted weight loss or to a comparison condition of diabetes support and education (DSE). Use and costs of health-care services were recorded across an average of 10 years.<h4>Results</h4>ILI led to reductio ...[more]