Ontology highlight
ABSTRACT:
SUBMITTER: Soysa R
PROVIDER: S-EPMC4142068 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Molecular and biochemical parasitology 20140527 1
Gene expression in kinetoplastid parasites is regulated via post-transcriptional mechanisms that modulate mRNA turnover, translation rate, and/or post-translational protein stability. To facilitate the analysis of post-transcriptional regulation, a dual luciferase system was developed in which firefly and Renilla luciferase reporters genetically fused to compatible drug resistance genes are integrated in place of one allele of the gene of interest and of an internal control gene, respectively, i ...[more]