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Assembly of heterogeneous functional nanomaterials on DNA origami scaffolds.

ABSTRACT: One on each side: gold nanoparticles (AuNPs) and semiconducting quantum dots (QDs) are integrated on a single DNA origami scaffold. Streptavidin-functionalized QDs bind to biotin anchors on one side of the DNA origami, while DNA-coated AuNPs bind through DNA hybridization to single-stranded DNA on the other side of the scaffold. This approach offers a new path toward the organization of complex systems consisting of disparate materials.

SUBMITTER: Wang R

PROVIDER: S-EPMC4144419 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Assembly of heterogeneous functional nanomaterials on DNA origami scaffolds.

Wang Risheng R Nuckolls Colin C Wind Shalom J SJ

Angewandte Chemie (International ed. in English) 20121010 45

One on each side: gold nanoparticles (AuNPs) and semiconducting quantum dots (QDs) are integrated on a single DNA origami scaffold. Streptavidin-functionalized QDs bind to biotin anchors on one side of the DNA origami, while DNA-coated AuNPs bind through DNA hybridization to single-stranded DNA on the other side of the scaffold. This approach offers a new path toward the organization of complex systems consisting of disparate materials. ...[more]

PMID: 23055455

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