Alternative dosage schedules with HPV virus-like particle vaccines.
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ABSTRACT:
SUBMITTER: Stanley MA
PROVIDER: S-EPMC4147727 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Publications
Alternative dosage schedules with HPV virus-like particle vaccines.
Stanley Margaret A MA Sudenga Staci L SL Giuliano Anna R AR
Expert review of vaccines 20140707 8
HPV vaccines can prevent multiple cancers in women and men. Difficulties in the cost and completion of the three-dose vaccine series have led to considerations of alternative dose schedules. In clinical trials, three doses given within a 12-month period versus the standard 6-month period yielded comparable results, and immunogenicity appears comparable with two doses in adolescent females compared to the three-dose series in adult females. While the data are generally supportive of moving to a t ...[more]
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