Ontology highlight
ABSTRACT:
SUBMITTER: Wen J
PROVIDER: S-EPMC4155498 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Wen Juyi J Liu Hongliang H Wang Qiming Q Liu Zhensheng Z Li Yangkai Y Xiong Huihua H Xu Ting T Li Peng P Wang Li-E LE Gomez Daniel R DR Mohan Radhe R Komaki Ritsuko R Liao Zhongxing Z Wei Qingyi Q
European journal of cancer (Oxford, England : 1990) 20140426 10
<h4>Background</h4>LIN28 is an RNA-binding protein that not only plays key roles in multiple cellular developmental processes and tumourigenesis, but also is involved in tissue inflammatory response. However, no published study has investigated associations between genetic variants in LIN28 and radiation-induced pneumonitis (RP) in patients with non-small cell lung cancer (NSCLC) treated with definitive radiation therapy.<h4>Methods</h4>We genotyped eight potentially functional single nucleotide ...[more]