Ontology highlight
ABSTRACT:
SUBMITTER: Zhao K
PROVIDER: S-EPMC4159230 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Zhao Kai K Wei Libin L Hui Hui H Dai Qinsheng Q You Qi-Dong QD Guo Qing-Long QL Lu Na N
PloS one 20140909 9
The patients diagnosed with melanoma have a bad prognosis for early regional invasion and distant metastases. Wogonin (5,7-dihydroxy-8-methoxyflavone) is one of the active components of flavonoids that extracts from Scutellariae radix. Several previous studies reported that wogonin possesses antitumor effect against leukemia, gastrointestinal cancer and breast cancer. In this study, we used melanoma cell B16-F10 to further investigate the anti-invasive and anti-migratory activity of wogonin. Our ...[more]