Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.
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ABSTRACT:
SUBMITTER: Cheetham AG
PROVIDER: S-EPMC4160079 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.
Cheetham Andrew G AG Ou Yu-Chuan YC Zhang Pengcheng P Cui Honggang H
Chemical communications (Cambridge, England) 20140428 45
We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the linker group of drug amphiphiles on the drug release efficiency and their consequent in vitro efficacy. ...[more]
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