Ontology highlight
ABSTRACT:
SUBMITTER: Kato HE
PROVIDER: S-EPMC4160518 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Nature 20120122 7385
Channelrhodopsins (ChRs) are light-gated cation channels derived from algae that have shown experimental utility in optogenetics; for example, neurons expressing ChRs can be optically controlled with high temporal precision within systems as complex as freely moving mammals. Although ChRs have been broadly applied to neuroscience research, little is known about the molecular mechanisms by which these unusual and powerful proteins operate. Here we present the crystal structure of a ChR (a C1C2 ch ...[more]