L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials.
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ABSTRACT:
SUBMITTER: Zhao F
PROVIDER: S-EPMC4160809 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials.
Zhao Fan F Heesters Balthasar A BA Chiu Isaac I Gao Yuan Y Shi Junfeng J Zhou Ning N Carroll Michael C MC Xu Bing B
Organic & biomolecular chemistry 20140901 35
An l-rhamnose-based hydrogelator self-assembles to form nanofibrils, which, in contrast to the properties of monomeric l-rhamnose, suppress the antibody response of mice to phycoerythrin (PE), a fluorescent protein antigen. As the first example of the supramolecular assemblies of a saccharide to suppress immunity, this work illustrates a new approach of immunomodulation. ...[more]
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