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¹?F NMR indicator displacement assay using a synthetic receptor with appended paramagnetic relaxation agent.


ABSTRACT: An admixture of zinc(II)-bis(dipicolylamine) receptor with covalently attached paramagnetic relaxation agent and fluorine-labeled phosphate indicator enables (19)F NMR detection of phosphorylated analytes with amplified switched-on signal intensity.

SUBMITTER: Plaunt AJ 

PROVIDER: S-EPMC4162400 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

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¹⁹F NMR indicator displacement assay using a synthetic receptor with appended paramagnetic relaxation agent.

Plaunt Adam J AJ   Clear Kasey J KJ   Smith Bradley D BD  

Chemical communications (Cambridge, England) 20140901 72


An admixture of zinc(II)-bis(dipicolylamine) receptor with covalently attached paramagnetic relaxation agent and fluorine-labeled phosphate indicator enables (19)F NMR detection of phosphorylated analytes with amplified switched-on signal intensity. ...[more]

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